Behavior and Health

Position: EN > Team > Behavior and Health > 正文
Li Rui, PhD
2017-08-10

Department of Nutrition and Food Hygiene, College of Public Health, Wuhan University
185 East Lake Rd, Wuhan, Hubei 430071
Tel: 86-18627149820
Email: lirui820@gmail.com

     

EDUCATION
The University of Tennessee, Knoxville, Tennessee, 2009-2013   Ph.D. in Nutritional Sciences

    Wuhan University, Wuhan, China, 2004-2008   B.S. in Biological Sciences

     

AWARDS and HONORS
Graduate Student Research Award, Experimental Biology, Boston, MA, 2013
Sadie K. Stanton Human Ecology Scholarship, the University of Tennessee, Knoxville, TN, 2012-2013
ESPN Nutrition Award, the University of Tennessee, Knoxville, TN, 2012-2013
ESPN Nutrition Award, the University of Tennessee, Knoxville, TN, 2011-2012
Inez Lovelace and LoVera Lovelace McKenney Scholarship, the University of Tennessee, Knoxville, TN, 2011-2012
Helen Sharp Hakala Scholarship, the University of Tennessee, Knoxville, TN, 2010-2011
Sadie K. Stanton Human Ecology Scholarship, the University of Tennessee, Knoxville, TN, 2009-2010
Outstanding Student Award, Wuhan University, Wuhan, China, 2007-2008
Outstanding Student Award, Wuhan University, Wuhan, China, 2006-2007
Outstanding Student Award, Wuhan University, Wuhan, China, 2004-2005

     

RESEARCH EXPERIENCE
Doctoral Research: Department of Nutrition, the University of Tennessee, 2009-2013 (research advisor: Dr. Guoxun Chen)
- Investigation of the mechanism of RA-induced Gck transcription.
- Investigation of roles of retinoids in the regulation of Srebp-1c expression.

    Undergraduate Research I: College of Life Sciences, Wuhan University, 2007-2008 (research advisor: Dr. Ying Zhu)
- Investigation of roles of IL-27 in influenza A virus infection.

    Undergraduate Research II: China Center For Type Culture Collection, Wuhan University, 2006-2007 (research advisor: Dr. Congyi Zheng)
- Cloning of the alternative splice variants of breast cancer susceptibility gene, Brca1.

 

PROFESSIONAL SOCIETIES
American Society for Nutrition
American Heart Association

     

PUBLICATIONS
1.Li, Y., Zhang, Y., Li, R., Chen, W., Howell, M., Zhang, R., and Chen, G. (2012). The Hepatic Raldh1 Expression Is elevated in Zucker Fatty Rats and Its Over-Expression Introduced the Retinal-Induced Srebp-1c Expression in INS-1 Cells. PLoS One 7, e45210.
2.Liu, L., Cao, Z., Chen, J., Li, R., Cao, Y., Zhu, C., Wu, K., Wu, J., Liu, F., and Zhu, Y. (2012). Influenza A Virus Induces Interleukin-27 through Cyclooxygenase-2 and Protein Kinase A Signaling. Journal of Biological Chemistry 287, 11899-11910.
3.Zhao, S., Li, R., Li, Y., Chen, W., Zhang, Y., and Chen, G. (2012). Roles of vitamin A status and retinoids in glucose and fatty acid metabolism. Biochem Cell Biol.
4.Zhang, Y., Chen, W., Li, R., Li, Y., Ge, Y., and Chen, G. (2011). Insulin-regulated Srebp-1c and Pck1 mRNA expression in primary hepatocytes from zucker fatty but not lean rats is affected by feeding conditions. PLoS One 6, e21342.
5.Ge, Y., Zhang, Y., Li, R., Chen, W., Li, Y., and Chen, G. (2011). Berberine regulated Gck, G6pc, Pck1 and Srebp-1c expression and activated AMP-activated protein kinase in primary rat hepatocytes. Int J Biol Sci 7, 673-684.
6.Zhang, Y., Li, R., Chen, W., Li, Y., and Chen, G. (2011). Retinoids induced Pck1 expression and attenuated insulin-mediated suppression of its expression via activation of retinoic acid receptor in primary rat hepatocytes. Mol Cell Biochem 355, 1-8.
7.Li, R., Chen, W., Li, Y., Zhang, Y., and Chen, G. (2011). Retinoids synergized with insulin to induce Srebp-1c expression and activated its promoter via the two liver X receptor binding sites that mediate insulin action. Biochem Biophys Res Commun 406, 268-272.
8.Liu, L., Li, R., Pan, Y., Chen, J., Li, Y., Wu, J., and Zhu, Y. (2011). High-throughput screen of protein expression levels induced by cyclooxygenase-2 during influenza a virus infection. Clin Chim Acta 412, 1081-1085.
9.Zhang, R., Zhu, C., Bai, L., Li, R., Cao, Y., He, H., You, J., Liu, Y., Liu, F., Wu, K., and Wu, J. (2012). Hepatitis B virus induces expression of collagen triple helix repeat containing 1, a key regulator in the development of hepatocellular carcinoma. (Submitted)
10.Li, R., Zhang, R., Chen, W., Li, Y., Howell, M., and Chen, G. (2013). The role of RARα, RXRα, HNF4α, and COUP-TFII in the transcriptional regulation of hepatic glucokinase gene expression. (Submitted)

     

PRESENTATIONS
1.Li, R. and Chen, G. (21 April 2012). Identification of the retinoic acid response element in hepatic glucokinase gene promoter. (Oral presentation) Experimental Biology 2012, San Diego, CA.
2.Li, R. and Chen, G. (2 March 2012). Determination of the retinoic acid response element in the liver glucokinase gene promoter using deletion and linker-scan analysis. (Oral presentation) Research Day 2012, Auburn University, Auburn, AL.
3.Li, R., Li, Y., and Chen, G. (11 April 2011) Regulatory Role of Retinoic Acid in Glucokinase and Sterol Regulatory Element-binding Protein-1c Expression. (Poster) Experimental Biology 2011, Washington, DC.
4.Li, R., and Chen, G. (25 April 2010) Zucker Lean and Fatty Rat Hepatocytes Respond Differently to Insulin and Retinoids in the Expression of Glucose and Lipid Metabolic Genes. (Poster) Experimental Biology 2010, Anaheim, CA.

     

     

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